Isoinokosterone when Doctor Burdette in 1963 found that Isoinokosterone enhanced the rate of protein synthesis. This was the beginning of over 50 studies showing the remarkable effects of Isoinokosterone on the body while simultaneously showing no side effects. Now, with the increased economical availability of pure concentrated Isoinokosterone, the picture is finally becoming more complete. Studies: Isoinokosterone has been tested for its effects on work capacity, immune function, lean body mass and fat loss, among other variables in a number of scientific studies. The vast majority of research indicates an increase in test subjects' lean mass. Results were further improved when Isoinokosterone was consumed with protein. Increase Protein Synthesis and Invoke Positive Nitrogen Balance Studies conducted in the Soviet Union in 1988 showed Isoinokosterone helps "increase hepatic protein synthesis and subsequently promote positive nitrogen balance!" How does this lead to more muscle mass? Simply: "the more nitrogen your body maintains and the greater rate of protein synthesis, the more mass, period." How, exactly, does ecdysterone do this? V. Smetanin, researcher of the Smolenk State Medical Institute in Russia speculates that Isoinokosterone decreases urea concentration in the body and increases hemoglobin levels by increasing a process called erythropoiesis. Erythropoiesis is the development of mature red blood cells. This leads to a stimulation of the anabolic process in protein metabolism, which in turn

Results were further improved. When Isoinokosterone was consumed with Increased protein. Because of herbs increases protein Synthesis and Invokes a Positive Nitrogen Balance Studies conducted in the Soviet Union in 1988 showed Isoinokosterone helps "increase hepatic protein synthesis and subsequently promote positive nitrogen balance!" How does this lead to more muscle mass? Simply: "the more nitrogen your body maintains and the greater rate of protein synthesis, the more mass, period." How, exactly, does ecdysterone do this?

These reports come from different websits.
V. Smetanin, researcher of the Smolenk State Medical Institute in Russia speculates that Isoinokosterone decreases urea concentration in the body and increases hemoglobin levels by increasing a process called erythropoiesis. Erythropoiesis is the development of mature red blood cells. This leads to a stimulation of the anabolic process in protein metabolism, which in turn leads to a positive nitrogen balance in the body.Increase Lean Muscle Mass While Reducing Body Fat The most often quoted Isoinokosterone scientific study was published in Scientific Sports Bulletin by S. Simakin in 1988. The objective of Simakin's famous study was to determine the effect of Isoinokosterone on muscle tissue mass and fat mass, while testing for hormonal changes in the subjects. For the study, three control factors were used: a placebo, protein, and Isoinokosterone with protein.

The results were significantly in favor of the third factor. Of the 78 highly trained male and female athletes who consumed just protein, they showed only a slight increase in muscle mass for the 10 day period of time. Those who used a placebo lost a slight amount of lean muscle, while those who used protein plus Isoinokosterone showed a 6-7% increase in lean muscle tissue with nearly a 10% reduction in fat! Let me say that again: A 10% reduction in fat and a 7% increase in lean muscle tissue in just 10 days! Safety testing was conducted during the same time period which showed no difference in hormonal balance.

Wow, if Isoinokosterone plus protein can do this. For highly trained athletes, just think what it can do for the average person! It's interesting to note the amount of Isoinokosterone these Soviet Studies used.

Dosages that have worked. According to Derek Cornelius, "Most of the experiments used 5 mg per kilogram of body mass per day as the dosage. So, the average person should consume 300-600 mg of Isoinokosterone capsules per day to meet this dosage. This compound is so non-toxic that this is a perfectly safe amount to consume. Who needs it and what are some symptoms of deficiency?

Bodybuilders, athletes and fitness enthusiasts. Will find the extra gains in lean muscle mass and reduction in body fat very beneficial. Based on all the research, Isoinokosterone looks to be not only incredibly effective as a performance enhancer on all facets, but also very safe. Since it is not a required nutrient, there are no symptoms of deficiency. However, if you would like to experience more energy and strength gains in less time than you've probably ever experienced, grab some Isoinokosterone and protein because you are the perfect candidate! Check out the section below to learn more on side effects and recommended dosages. How much should be taken? Are there any side effects?

What about side effects? That's the best part! As you already know by now, research studies show no negative side effects, no hormonal interactions, and a very low toxicity level for Isoinokosterone. When tested by ICN Biochemicals on December 31, 1998, a complete safety test was performed to determine the toxicity. The data showed the amount of Isoinokosterone one would have to take in order to reach toxicity. The amount? 6400 mg/kg! In other words, an average 170lb person would have to take 494,528 mg of the compound to reach this point! This is 4,121 times as much as the recommended dose. So, as you can see, it's very safe with an incredibly low toxicity.

Furthermore, Isoinokosterone testing showed that Isoinokosterone caused no effect whatsoever on the mammalian hormonal system. Testing was measured on testosterone, cortisol, insulin, ACTH, growth hormone, and leutinizing hormone.

The data not only shows Isoinokosterone to be extremely safe. But effective as well! The recommended dose of Isoinokosterone is 80-120 mg per day and upwards of 400-600 mg per day. We've even heard reports of people receiving amazing results working up to using as much as 1200 mg safely per day. In the 1970’s the former Soviet Union decided to become involved with the compound as a way to enhance their athletes and still beat drug tests. Many papers were published on Isoinokosterone in the subsequent years which convincingly showed its anabolic effects. Most of the experiments used 5mg per kilogram of body mass per day as the dosage. The effects were evaluated by measurements of the increased mass, total protein, and glycogen content of specific muscles (i.e. levator ani and tibialis anterior). As before, the results were compared against the effects of true vertebrate anabolic steroids.

Compared with Anabolic steroids. For instance, a researcher named Chermnykh compared the effects of Isoinokosterone and Methandrostenolone (a very potent anabolic steroid) in mice and found some astounding results. These compounds were given to two parallel experimental sets of mice for seven days—one untrained and the other subjected to training in the form of repeated swimming. Chermnykh found that both compounds caused anabolic increases of body mass only under the conditions of temporary training. Although Isoinokosterone generally stimulated physical capability for labour, Methandrostenolone could do the same only in association with temporary training. Methandrostenolone stimulated biosynthesis of the myofibrilar proteins in the musculus soleus but not in the musculus extensor digitorum longus, while Isoinokosterone increased the myofibrilar proteins in both muscles. Similar results have been confirmed in other vertebrate species consuming Isoinokosterone such as various birds, cattle, pigs, and even humans!

Besides the clear anabolic effects of Isoinokosterone.
Let us now look at the myriad of other positive benefits of this incredible compound. Because of the anabolic similarities between anabolic steroids and Isoinokosterone a researcher named Yoshida decided to see if there were any other similarities. In 1971 he studied whether Isoinokosterone would educe the hyperglycemic response to exogenous glucagons.

As expected, Isoinokosterone had a suppressive effect on hyperglycemia. Interestingly, it did not affect those animals that had normal blood sugar levels. Furthermore, even though the blood sugar levels were unaffected in normal animals, it did stimulate the incorporation of glycogen into proteinaceous tissue such as liver and muscle.

The scenario couldn’t be more ideal! Here we have a compound that will powerfully stabilize your blood sugar levels and at the same time “feed” your muscles and organs with energy-giving glycogen. Isoinokosterone is the perfect glycemic regulator. It will not only prevent you from having high blood sugar levels but also high insulin levels. High insulin levels stimulate lipogenesis—a process which basically makes you gain fat mass. With steady and even insulin levels, these fat-producing processes are halted in their tracks. Even blood sugar levels also are integral in the feeling of well being for a person as it ensures constant energy levels.

Finally, Isoinokosterone actually pushes. Nutrients into muscle and organ tissue allowing for accelerated growth.Some of you might be saying, “WOW!” right now, but it gets even better. For instance, Isoinokosterone has a potent cholesterol lowering effect that is brought on by increasing cholesterol secretion in the bile as well as inhibiting de novo synthesis of cholesterol. While studying this effect, researches found that Isoinokosterone produced profound increases in the specific activity of phosphatidyl-ethanolamine and phosphyatidyl-serine.

These phospholipids are integral to nearly every bodily process and are linked to enormous health benefits when they are stimulated.

A final benefit of Isoinokosterone. That was discovered while studying the cholesterol lowering effect was a potent hepatoprotective action. This is good news in light of the many potentially harmful compounds we ingest everyday in our highly processed environment.The good news hasn’t stopped yet! Isoinokosterone also has beneficial effects on the cardiovascular system. Because of its cell membrane stabilizing properties, Isoinokosterone has distinct anti-arrhythmia effects on the heart as well as a restorative action atherosclerosis. In fact, researchers have witnessed overall improvements in the hemodynamic conditions of the heart as well as heart contractility.
Continuing along, Isoinokosterone has been also demonstrated to have analgesic properties as well as potent antioxidative properties. An important effect of Isoinokosterone for sports enhancement is its powerful anti-inflammatory properties. Almost too good to be true, Isoinokosterone has been shown to be as potent as cortisone acetate on specific inflammatory responses. We thus see Isoinokosterone as an agent that works against high cortisol levels. How so? Well, glucocorticoids like cortisol are released in response to stressors such as inflammation.

By actively reducing or eliminating many of these stressors, Isoinokosterone prevents cortisol from being released from the adrenals. Since glucocorticoids are catabolic to proteinaceous tissue, it is highly beneficial to do whatever you can to restrict their release.

A final effect that is hinted at in the literature but not fully elucidated is Isoinokosterone’s effect on the skin. Some research shows a positive effect on keratinization and differentiation but beyond that—nothing! I have seen, first hand, its positive effects on acne and believe me it is quite amazing. Even better is the fact that positive results can be seen within a few days. Combined with a high quality guggul extract, incredible improvements can be seen towards blemish-free skin.

My guess would be that Isoinokosterone would also be an effective agent against psoriasis although I have no specific knowledge of it working therapeutically for this purpose.One of the greatest things about Isoinokosterone is its utmost safety profile. Lately, some scoundrels in the industry are gung-ho on calling everything poisonous and dangerous that they do not distribute (you got it—they are supplement manufacturers). Unfortunately, they do a ton of damage to this industry by spreading their false information. Isoinokosterone though is beyond reproach.

You would be hard pressed to find even one small detail that was negative about Isoinokosterone. In fact, it is so safe that the LD50 in mice is 9grams per kilogram. At this level, an adult male would have to consume nearly one kilogram of Isoinokosterone to have a good chance of killing you! Since, Isoinokosterone is recommended at a dosage of 500mg per day, there is basically zero chance of any problems.“All of this research is great”, you say, “but what about real world results?” Some of you might remember that many years ago several companies were distributing a Suma extract that had Isoinokosterone in it. A whole handful of pills would only profit you less than 50mg of Isoinokosterone. Not only was the Isoinokosterone not very bioavailable but the dosage was way too low for noticeable results.

The dilemma with this dietary supplement has always been obtaining a high potency, pure or semi-pure product that was priced reasonably. For years, there were only two choices: the ineffective Suma extract and pure Isoinokosterone from Russia that cost $20,000 per kilogram. Although effective, it would cost you about $50.00 per day retail to use it in sufficient quantity.

Several years ago, I became very interested in this compound and began looking into all the possibilities of obtaining a high-potency, economical product.

About a year ago, I started working with an Israeli company on a new process that would produce Isoinokosterone from an in vitro cell culture system. This process is extremely high-tech and yields a large amount product at a very cheap price. Finally, in the 20th century we are able to reap the benefits of this awesome compound.At this point, real world results are restricted to the trials that the Russians did on this compound as well as the 20,000 people who have bought the new, pure version that is now available in the U.S. I communicated with several Russian researchers who extensively studied this compound on world-class athletes. Combined, they experimented on about 65 athletes.

My staff and I have also communicated with at least 300 individuals. None of the reports that we received indicated any negative side effects. Furthermore, nearly every person, including the Russian scientists, indicated that they noticed significant increases in lean body mass, endurance, strength and feelings of well-being.

Several experienced bodybuilders that I talked with indicated that they did better on Isoinokosterone than anything else except high dosages of anabolic steroids. One runner that I talked to shaved two minutes off his best time! Finally, a female fitness competitor gained 3 pounds of lean body mass while becoming significantly leaner. As you can see, Isoinokosterone is truly a revolutionary supplement. Not only does it vastly increase athletic performance but it improves nearly every bodily process.
This is very unusual in a compound that does all of this. Usually, like anabolic steroids, the many positive aspects will be somewhat offset by the few negative ones. Isoinokosterone, however, powerfully assists you in your goals while simultaneously improving every aspect of your health. It might not be magic, but Isoinokosterone is the best “bug juice” I have every seen! Question: All I have to say is that this website rocks dude! I used to frequent another supposedly hardcore website but they became nothing but a bunch of sellouts. You guys know your stuff inside and out. Let me tell you right now that I know what I’m doing. I rock climb for a living and I don’t play games. Sometimes I climb totally free. When you’re all alone and it’s just you and the rocks you better be 100% confident in your abilities. I take this stuff seriously. A few months ago I read on your website about those bug hormones.

I’ve taken about every supplement on the market so I know what to expect. Well, I bought some but it took me totally by surprise. Within days I noticed that my climbing was taking on a renewed vigor. My mind/muscle connection was better, I was stronger and I felt like I had suction cups on my fingers. I could’ve swore that the rocks and I were one. Is it possible for you to tell me what other feedback that you have received on this stuff? Answer: The stuff that you are talking about is called Isoinokosterone or 20-hydroxyecdysterone. Whatever the name, this dietary supplement is truly revolutionary.

I will tell you that the research shows that it is as strong as Dianabol and 4-Chlorotestosterone. I will tell you that there are many studies which show this. I will also tell you that in real life, it is just not that strong. Disappointed? You shouldn’t be. Isoinokosterone may not be as strong as many anabolic steroids but it is stronger than 99% of the supplements on the market. Once in a while, I will receive a report from someone that did not get good results. However, this is to be expected.

There are many lazy people out there whose diets and exercise programs are pitiful. I don’t care what you are taking, if your diet and exercise program stinks then your results will stink. I like to ask people, “What are you all about?” If you are about results, if you are about working hard, if you are about eating right, then Isoinokosterone is the perfect supplement for you. From the feedback I receive, Isoinokosterone works great for about 90% of the people who use it. These are phenomenal results and I couldn’t be happier.

Better Muscle pumps. The people that I talk to report increased hardness and vascularity as well as better muscle pumps. Vastly decreased recovery time is also a common reported side effect. Just the other day, I talked to a guy that cut his recovery time in half by supplementing with Isoinokosterone. In terms of putting on sheer muscle mass, 3-5 pounds seems to be the going numbers. The great thing about Isoinokosterone is that it induces results you can really see and feel.

Better than Creatine. These are not results like creatine which are noticeable but which are attributable to water weight and which dissipate upon ceasing its usage. The results you obtain with Isoinokosterone are at least semi-permanent as they are due to real changes to the muscle and not just water weight.

INTRODUCING THE RUSSIAN BREAKTHROUGH. In steroidal nutrient sports performance! For decades large pharmaceutical companies have been searching for the "steroidal Holy Grail." This compound would not only potently stimulate the growth of lean body mass but would significantly escape first pass liver metabolism.

Furthermore, it would have no negative side effects--no virilization, no conversion into estrogenic compounds, no liver toxicity, no high blood pressure and no testicular shrinkage. Meet Isoinokosterone (Ecdysterone)--the "Holy Grail" of dietary supplements.

With the help of top scientists in Russia, Syntrax brings you this perfect dietary supplement. Research shows that in vertebrates, the active component in Syntra-EC drastically increases lean body mass and endurance, decreases blood sugar levels and adipose tissue, and improves nearly every bodily process, including liver and brain function.

Best of all, it is safe for men and women...including teenagers! In the late 60’s, some forward thinking Japanese scientists by the name of Okui and Otaki studied the effects of Isoinokosterone on protein synthesis in male and female mouse liver. In these experiments, the results were compared against the protein stimulating actions of 4-chlorotestosterone, a potent anabolic steroid.

Amazingly, the time-course of change induced by Isoinokosterone and 4-chlorotestosterone was similar, with a maximum effect of 200% of controls observed after 5 hours and a return to initial levels after 12 hours.
Many similar studies were performed which verified these results including ones which showed that the protein stimulation occurred in both the microsomal and polysomal fractions. Other studies in ’69 and ’84 showed that Isoinokosterone even stimulates protein synthesis in nervous tissue and increases nerve function. Obviously, the implications of this research are far-reaching.